Very proud to receive the 2023 Award for the Biophysics of Health and Disease from the Biophysical Society at this year's society meeting! This award recognizes a long-running project in my lab and our collaborators to develop a small molecule drug targeting hypoxia inducible factor 2 (HIF-2), leveraging biophysical information on a novel cavity [...]
Welcome to Ramisha Aymon & Anastasiia Fisiuk, two CCNY undergrads who've joined the lab for one year honors dissertation work through the CCNY Department of Chemistry & Biochemistry. Ramisha's been associated with the lab for awhile – but unable to join in many things due to COVID restrictions – and Anastasiia's new to us. [...]
Congrats to Joey Closson, a second year Ph.D. student in the lab, for passing his second level exam for the CUNY GC Ph.D. Program in Biochemistry. This exam, comparable to "qualifying exams" in many other Ph.D. programs, is focused on a written research proposal and its oral defense – and marks the last of the [...]
It's always a treat to sit down with friends to talk shop, and I've been privileged to recently be asked to be part of two such conversations that have turned into podcast episodes: in mid-December, I had a fantastic, far-ranking discussion on research and teaching with Kaylan Chakrabarti at Krea University (https://twitter.com/kschakrabarti) while I was [...]
Final entry in a series of three aspects I've been particularly proud of this year: Impactful ideas that have taken some time to come to fruition, and those who've been key parts of long stints of the almost 25(!) years since the lab opened in August 1998. A great example of this has been [...]
Second entry in a series of three aspects I've been particularly proud of this year: Having a fantastic team of Ph.D. students in the group from the Graduate Center's Ph.D. programs in Biochemistry and Biology: Jim Xu, Roksana Azad, Matt Cleere, Danielle Swingle, Jimmy Siclari, Tarsisius Tiyani, and Joey Closson (all detailed here). Great to [...]
First entry in a series of three aspects I've been particularly proud of this year: Having some great undergrads come through the group this year, whether for a summer through the CCNY B3 REU program (including Keerthana Rameshbabu and Marina Shi in 2022) or through the CCNY Chemistry & Biochemistry Department's Honors Research Program. Very [...]
As part of the CUNY Graduate Center's Science In The City series, I had the privilege of hosting a one-on-one interview with UT Southwestern's Mike Brown in April 2022 to discuss some key aspects of the drug discovery process. This was a real treat for many reasons, having known Mike for over twenty years [...]
Congratulations to Jim Xu, winner of the 2022 Horst Schulz Award from the CUNY Ph.D. Program in Biochemistry, given each year to the student in the program with the best first-authored paper of the preceding year. Jim's Biophysical Journal paper "Volume and Compressibility Differences Between Protein Conformations Revealed by High-Pressure NMR" was an elegant [...]
Catching up on some great news from earlier in the summer – congratulations to both Kaitlyn Toy and Leandro Pimentel Marcelino, two CCNY Biochemistry graduates who'd done undergraduate honors dissertations in my group earlier in their careers. Kaitlyn, who was in the Macaulay Honors College and won the department's Ward Medal for best academic record, did her [...]